Olmesartan Associated Sprue-Like Enteropathy and Colon Perforation

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Olmesartan Associated Sprue-Like Enteropathy and Colon Perforation

We are reporting a unique case of olmesartan associated severe sprue-like enteropathy in a 52-year-old woman who presented to our hospital complaining of severe abdominal pain and nausea. At the emergency department she suffered from a cardiac arrest and was found to have a colon perforation. The patient was treated conservatively without surgical intervention and olmesartan was discontinued. A...

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Severe sprue-like enteropathy associated with olmesartan.

OBJECTIVE To report the response to discontinuation of olmesartan, an angiotensin II receptor antagonist commonly prescribed for treatment of hypertension, in patients with unexplained severe spruelike enteropathy. PATIENTS AND METHODS All 22 patients included in this report were seen at Mayo Clinic in Rochester, Minnesota, between August 1, 2008, and August 1, 2011, for evaluation of unexpla...

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Olmesartan-Induced Sprue Like Enteropathy

Chronic diarrhoea is a common clinical problem in gastroenterology practice and often it is difficult to diagnose the cause. Villous atrophy is not specific and the rarer possibility of drug-induced enteritis should always be considered. Olmesartan has recently been described as a cause of drug-induced enteropathy characterized by chronic diarrhoea and varying degrees of duodenal mucosa atrophy...

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Systematic review: Sprue-like enteropathy associated with olmesartan.

BACKGROUND The onset of a sprue-like enteropathy in association with olmesartan therapy has been recently reported. AIMS To perform a systematic review of the literature and describe three additional cases of olmesartan-associated enteropathy. METHODS Electronic and manual bibliographic searches were performed to identify original reports in which subjects who were undertaking olmesartan de...

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Sprue-Like Enteropathy Associated with Olmesartan: An Unrecognized Emerging Drug-Induced Enteropathy?

F 72 2014 Chronic diarrhea; abdominal discomfort 6 months Normocytic anemia; hypoK; hypoAlb Clinical remission 3 months Yes features and share our small case-series experience (Table 1). Curiously, in both cases symptoms developed long (fourteen and ten months, respectively) after starting therapy. This has rarely been addressed and may difficult the diagnosis. The primary care physicians were ...

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ژورنال

عنوان ژورنال: Case Reports in Gastrointestinal Medicine

سال: 2014

ISSN: 2090-6528,2090-6536

DOI: 10.1155/2014/494098